Growth hormone axis treatments for HIV‐associated lipodystrophy: a systematic review of placebo‐controlled trials
T. Sivakumar, Oj Mechanic, DA Fehmie, Bt Paul•September 1, 2011•29 citations
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Abstract
Our review indicates that, based on the findings of the 10 included studies, GH axis treatments are effective in reducing VAT and increasing LBM in patients with HIV-associated lipodystrophy. However, clinicians must decide whether the attributed benefits are clinically significant, considering the costs and potential risks of GH axis treatments. A limitation of this study is the small number of studies available of each GH axis drug class.